Services > Analytical & Bioanalytical Services
Alytical & Bioanalytical Services
Analytical and Bioanalytical Services

We use state-of-the-art instrumentation to support projects in medicinal chemistry, process development, drug formulation, preclinical and clinical drug development, and quality control of raw ingredients. To request any of our services, please download our analytical services submission form..

Our analytical services include:

  • chromatographic separation
  • quantitation of major and minor components in raw API and formulated drug products
  • identification of impurities generated during manufacturing, stress testing, and stability studies
  • analytical support for the design, synthesis, and scale-up of new chemical entities
  • development of qualitative and quantitative analytical methods in HPLC, LC/MS or LC-MS/MS for support of preclinical drug discovery studies
  • method qualification
  • acquisition, processing and reporting of preclinical and pharmacokinetic and toxicokinetic data, including ADME, protein binding and metabolites identification
  • development of qualitative and quantitative bio-analytical methods using LC-MS/MS (Applied Biosystems/MDS SCIEX API 4000 triple quadrupole mass spectrometer) for small molecules and metabolites in biological matrices (plasma, urine, and various tissues)
  • analytical support for pharmacokinetics studies, dose formulation and dose verification, metabolite identification, stability, solubility, and other experimental needs
  • development of small molecule extraction protocols for various biological matrices using liquid-liquid extraction (LLE), solid phase extraction (SPE) and protein precipitation techniques.
  • PK data generation and interpretation for non-compartmental analysis using WinNonlin software.
  • 96-well sample processing and analysis.
 
shazampowgotcha